Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50279316'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50279316 (CHEMBL4167668) Show SMILES COc1cc2ncc(-c3ccc4[nH]ncc4c3)n2cc1S(=O)(=O)C(C)(C)C Show InChI InChI=1S/C19H20N4O3S/c1-19(2,3)27(24,25)17-11-23-15(10-20-18(23)8-16(17)26-4)12-5-6-14-13(7-12)9-21-22-14/h5-11H,1-4H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of full length RIPK2 (unknown origin) pretreated for 30 mins followed by ATP addition measured after 2 hrs by ADP-d2 tracer based fluoresc...				ACS Med Chem Lett 8: 1048-1053 (2017) Article DOI: 10.1021/acsmedchemlett.7b00258 BindingDB Entry DOI: 10.7270/Q2ST7SBP
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50279316 (CHEMBL4167668) Show SMILES COc1cc2ncc(-c3ccc4[nH]ncc4c3)n2cc1S(=O)(=O)C(C)(C)C Show InChI InChI=1S/C19H20N4O3S/c1-19(2,3)27(24,25)17-11-23-15(10-20-18(23)8-16(17)26-4)12-5-6-14-13(7-12)9-21-22-14/h5-11H,1-4H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of RIPK2 in human PBMCs assessed as reduction in MDP-stimulated IL8 secretion measured after 18 hrs				ACS Med Chem Lett 8: 1048-1053 (2017) Article DOI: 10.1021/acsmedchemlett.7b00258 BindingDB Entry DOI: 10.7270/Q2ST7SBP
					More data for this Ligand-Target Pair