Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50504963'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50504963 (CHEMBL4551566) Show SMILES [H][C@]12CC[C@]([H])(C1)Nc1c(C(N)=O)c(nn1C2)-c1ccc2scnc2c1 |r| Show InChI InChI=1S/C17H17N5OS/c18-16(23)14-15(10-2-4-13-12(6-10)19-8-24-13)21-22-7-9-1-3-11(5-9)20-17(14)22/h2,4,6,8-9,11,20H,1,3,5,7H2,(H2,18,23)/t9-,11+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length FLAG/His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system after 10 mins by fluorescent polarization...				ACS Med Chem Lett 10: 1518-1523 (2019) Article DOI: 10.1021/acsmedchemlett.9b00141 BindingDB Entry DOI: 10.7270/Q2R49V11
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50504963 (CHEMBL4551566) Show SMILES [H][C@]12CC[C@]([H])(C1)Nc1c(C(N)=O)c(nn1C2)-c1ccc2scnc2c1 |r| Show InChI InChI=1S/C17H17N5OS/c18-16(23)14-15(10-2-4-13-12(6-10)19-8-24-13)21-22-7-9-1-3-11(5-9)20-17(14)22/h2,4,6,8-9,11,20H,1,3,5,7H2,(H2,18,23)/t9-,11+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of RIPK2 in MDP-stimulated human whole blood assessed as TNF-alpha level preincubated for 30 mins followed by MDP stimulation and measured...				ACS Med Chem Lett 10: 1518-1523 (2019) Article DOI: 10.1021/acsmedchemlett.9b00141 BindingDB Entry DOI: 10.7270/Q2R49V11
					More data for this Ligand-Target Pair