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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50574935'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM50574935
PNG
(CHEMBL4866182)
Show SMILES CN[C@H](C)C(=O)N[C@@H](C(=O)N1C[C@H](C[C@H]1c1nc(cs1)C(=O)c1ccc(F)cc1)NC(=O)c1cnc(cn1)N1CCN(CCCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(C)(C)C |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.158n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01118
BindingDB Entry DOI: 10.7270/Q2VD739F
More data for this
Ligand-Target Pair