Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM476705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476705 (5-chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethyl...) Show SMILES COc1cc2c(c[nH]c2cc1C)-c1nc(Nc2cc(CN3C[C@H](C)N[C@H](C)C3)cc(c2)C2CC2)ncc1Cl Show InChI InChI=1S/C30H35ClN6O/c1-17-7-27-24(11-28(17)38-4)25(12-32-27)29-26(31)13-33-30(36-29)35-23-9-20(8-22(10-23)21-5-6-21)16-37-14-18(2)34-19(3)15-37/h7-13,18-19,21,32,34H,5-6,14-16H2,1-4H3,(H,33,35,36)/t18-,19+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0KQ4
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476705 (5-chloro-N-(3-cyclopropyl-5-(((3R,5S)-3,5-dimethyl...) Show SMILES COc1cc2c(c[nH]c2cc1C)-c1nc(Nc2cc(CN3C[C@H](C)N[C@H](C)C3)cc(c2)C2CC2)ncc1Cl Show InChI InChI=1S/C30H35ClN6O/c1-17-7-27-24(11-28(17)38-4)25(12-32-27)29-26(31)13-33-30(36-29)35-23-9-20(8-22(10-23)21-5-6-21)16-37-14-18(2)34-19(3)15-37/h7-13,18-19,21,32,34H,5-6,14-16H2,1-4H3,(H,33,35,36)/t18-,19+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
HANMI PHARM. CO.. LTD. US Patent					Assay Description The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...				US Patent US10870639 (2020) BindingDB Entry DOI: 10.7270/Q20G3P70
					More data for this Ligand-Target Pair