Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50277622'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277622 (CHEMBL4162390) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(nc2C)N(C)C)c(OC)c1 Show InChI InChI=1S/C18H21N5O2S/c1-11-16(26-18(20-11)23(2)3)14-8-9-19-17(22-14)21-13-7-6-12(24-4)10-15(13)25-5/h6-10H,1-5H3,(H,19,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair