Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50277648'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277648 (CHEMBL4159419) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCc3cccnc3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H21N5O2S2/c1-14-20(31-22(25-14)30-13-15-5-4-9-23-12-15)18-8-10-24-21(27-18)26-17-7-6-16(28-2)11-19(17)29-3/h4-12H,13H2,1-3H3,(H,24,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Binding affinity determined against ETA receptor in porcine aortic smooth muscle membrane				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair