Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50564363![]() (CHEMBL4791998) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human FLT3 D835Y mutant in presence of ATP | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112205 BindingDB Entry DOI: 10.7270/Q2VM4H1R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50564363![]() (CHEMBL4791998) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112205 BindingDB Entry DOI: 10.7270/Q2VM4H1R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50564363![]() (CHEMBL4791998) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | <0.25 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human FLT3 ITD mutant in presence of ATP by Lanthascreen Eu kinase binding assay | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112205 BindingDB Entry DOI: 10.7270/Q2VM4H1R | |||||||||||
More data for this Ligand-Target Pair |