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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase alpha' and Ligand = 'BDBM50135673'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein phosphatase alpha


(Homo sapiens (Human))		BDBM50135673
PNG
(3-Diethylaminomethyl-pyrimido[5,4-e][1,2,4]triazin...)
Show SMILES CCN(CC)Cc1nnc2nc(N)nc(N)c2n1
Show InChI InChI=1S/C10H16N8/c1-3-18(4-2)5-6-13-7-8(11)14-10(12)15-9(7)17-16-6/h3-5H2,1-2H3,(H4,11,12,14,15,17)
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PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration required against Protein-tyrosine phosphatase alpha in the presence of 300 nM DTT

Bioorg Med Chem Lett 13: 2895-8 (2003)


BindingDB Entry DOI: 10.7270/Q21V5DDS
More data for this
Ligand-Target Pair