Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase zeta' and Ligand = 'BDBM50464774'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein phosphatase zeta (Homo sapiens)	BDBM50464774 (CHEMBL4285322) Show SMILES FC(F)(F)S(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1 Show InChI InChI=1S/C16H11F6NO5S2/c17-15(18,19)29(25,26)12-5-1-10(2-6-12)9-14(24)23-11-3-7-13(8-4-11)30(27,28)16(20,21)22/h1-8H,9H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad San Pablo-CEU Curated by ChEMBL					Assay Description Inhibition of human recombinant PTPRZ1 using pNPP as substrate by fluorescence spectrometric analysis				Eur J Med Chem 144: 318-329 (2018) Article DOI: 10.1016/j.ejmech.2017.11.080 BindingDB Entry DOI: 10.7270/Q2C53PHW
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