Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive binding affinity to human RXFP4 receptor transfected in CHO-K1 cells in presence of europium-labeled Eu(A)-R3/I5 by fluorometric analysis | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00435 BindingDB Entry DOI: 10.7270/Q20Z76W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human RXFP4 expressed in CHO-K1 cells assessed as reduction in forskolin-induced cAMP production by pCRE beta-galactosidase repor... | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human RXFP4 expressed in CHO-K1 cells assessed as reduction in forskolin-induced cAMP production by pCRE beta-galactosidase repor... | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human RXFP4 transfected in CHO-K1 cells co-transfected with pCRE-beta-galactosidase reporter plasmid assessed as inhibition of fo... | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00435 BindingDB Entry DOI: 10.7270/Q20Z76W2 | |||||||||||
More data for this Ligand-Target Pair |