Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50427567'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50427567 (CHEMBL2322609) Show SMILES COCCCOc1cc(ccc1OC)C(=O)N(CC1CNCC1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H36N2O4/c1-34-16-9-17-36-29-19-24(14-15-28(29)35-2)30(33)32(27-12-7-4-8-13-27)22-26-21-31-20-25(26)18-23-10-5-3-6-11-23/h3-8,10-15,19,25-26,31H,9,16-18,20-22H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...				J Med Chem 56: 2207-17 (2013) Article DOI: 10.1021/jm3017078 BindingDB Entry DOI: 10.7270/Q2FB5487
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