Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicase polyprotein 1ab (2019-nCoV) | BDBM423462 (US11753373, Compound A-5-a | WO2006061714, P38.2 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.18 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2Z89HJV | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM423462 (US11753373, Compound A-5-a | WO2006061714, P38.2 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1039/d1md00247c BindingDB Entry DOI: 10.7270/Q2HH6Q3R | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...) | BDBM423462 (US11753373, Compound A-5-a | WO2006061714, P38.2 |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2005113580 | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Pfizer Inc. | Assay Description Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ... | WIPO (2005) BindingDB Entry DOI: 10.7270/Q2PV6NRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (SARS coronavirus Urbani) | BDBM423462 (US11753373, Compound A-5-a | WO2006061714, P38.2 |...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2006061714 | n/a | n/a | n/a | n/a | 1.40E+6 | n/a | n/a | n/a | n/a |
Pfizer Inc. | Assay Description Proteolytic activity of Coronavirus 3C protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS 3CI_pro FRET as... | WIPO (2006) BindingDB Entry DOI: 10.7270/Q22V2K5W | |||||||||||
More data for this Ligand-Target Pair |