Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicase polyprotein 1ab (2019-nCoV) | BDBM448358 (Perampanel, 12) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair |