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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit' and Ligand = 'BDBM50080859'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replication protein A 70 kDa DNA-binding subunit


(Homo sapiens (Human))		BDBM50080859
PNG
(CHEMBL3422464)
Show SMILES OC(=O)c1cc(-c2cccc(CNCc3ccc(cc3)-c3ccc(o3)C(O)=O)c2)n(n1)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C29H21Cl2N3O5/c30-22-9-8-21(13-23(22)31)34-25(14-24(33-34)28(35)36)20-3-1-2-18(12-20)16-32-15-17-4-6-19(7-5-17)26-10-11-27(39-26)29(37)38/h1-14,32H,15-16H2,(H,35,36)(H,37,38)
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Similars
Article
PubMed
n/an/an/a 57n/an/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity to RPA70N protein (unknown origin) incubated for 1 hr using FITC-ATRIP/FITC-ATRIP2 peptide probe by fluorescence polarization anisot...

ACS Med Chem Lett 6: 140-5 (2015)


Article DOI: 10.1021/ml5003629
BindingDB Entry DOI: 10.7270/Q2HM5B5R
More data for this
Ligand-Target Pair