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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50470148'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50470148
PNG
(CHEMBL42078)
Show SMILES CN(C)CCCOc1ccc(NC(=O)Cc2ccc(Cl)cc2C(=O)c2ccccc2)c(C)c1
Show InChI InChI=1S/C27H29ClN2O3/c1-19-16-23(33-15-7-14-30(2)3)12-13-25(19)29-26(31)17-21-10-11-22(28)18-24(21)27(32)20-8-5-4-6-9-20/h4-6,8-13,16,18H,7,14-15,17H2,1-3H3,(H,29,31)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 752n/an/an/an/an/an/a



Glaxo Research and Development Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase

J Med Chem 38: 1657-65 (1995)


Article DOI: 10.1021/jm00010a010
BindingDB Entry DOI: 10.7270/Q27947DP
More data for this
Ligand-Target Pair