Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50533359'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533359 (CHEMBL4472917) Show SMILES COc1ccc(cc1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-5-3-4-13(10-14)12-6-8-15(25-2)9-7-12/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533359 (CHEMBL4472917) Show SMILES COc1ccc(cc1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-5-3-4-13(10-14)12-6-8-15(25-2)9-7-12/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533359 (CHEMBL4472917) Show SMILES COc1ccc(cc1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-5-3-4-13(10-14)12-6-8-15(25-2)9-7-12/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533359 (CHEMBL4472917) Show SMILES COc1ccc(cc1)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C18H17N3O4/c1-20-16(11-17(22)21(24)18(20)23)19-14-5-3-4-13(10-14)12-6-8-15(25-2)9-7-12/h3-11,19,24H,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair