Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50533377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533377 (CHEMBL4475877) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-6-7-14(15(9-13)26-2)11-4-3-5-12(8-11)19-16-10-17(22)21(24)18(23)20-16/h3-10,19,24H,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533377 (CHEMBL4475877) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-6-7-14(15(9-13)26-2)11-4-3-5-12(8-11)19-16-10-17(22)21(24)18(23)20-16/h3-10,19,24H,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533377 (CHEMBL4475877) Show SMILES COc1ccc(c(OC)c1)-c1cccc(Nc2cc(=O)n(O)c(=O)[nH]2)c1 Show InChI InChI=1S/C18H17N3O5/c1-25-13-6-7-14(15(9-13)26-2)11-4-3-5-12(8-11)19-16-10-17(22)21(24)18(23)20-16/h3-10,19,24H,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair