Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50533403'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533403 (CHEMBL4563882) Show SMILES COc1ccc(cc1OC)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(9-14)13-7-8-15(26-2)16(10-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533403 (CHEMBL4563882) Show SMILES COc1ccc(cc1OC)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(9-14)13-7-8-15(26-2)16(10-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533403 (CHEMBL4563882) Show SMILES COc1ccc(cc1OC)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(9-14)13-7-8-15(26-2)16(10-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533403 (CHEMBL4563882) Show SMILES COc1ccc(cc1OC)-c1cccc(Nc2cc(=O)n(O)c(=O)n2C)c1 Show InChI InChI=1S/C19H19N3O5/c1-21-17(11-18(23)22(25)19(21)24)20-14-6-4-5-12(9-14)13-7-8-15(26-2)16(10-13)27-3/h4-11,20,25H,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair