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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50550018'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM50550018
PNG
(CHEMBL4782907)
Show SMILES Cn1c(=O)ccn(CCOc2cc(OS(F)(=O)=O)ccc2Oc2cccn3cc(cc23)C#N)c1=O
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 164n/an/an/an/an/an/a


TBA

Assay Description
Covalent inhibition of recombinant wild type HIV-1 reverse transcriptase using poly(rA)350/oligo(dT)16 as template/primer preincubated followed by su...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00612
BindingDB Entry DOI: 10.7270/Q2ZC86HB
More data for this
Ligand-Target Pair
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM50550018
PNG
(CHEMBL4782907)
Show SMILES Cn1c(=O)ccn(CCOc2cc(OS(F)(=O)=O)ccc2Oc2cccn3cc(cc23)C#N)c1=O
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.12E+3n/an/an/an/an/an/a


TBA

Assay Description
Covalent inhibition of recombinant wild type HIV-1 reverse transcriptase using poly(rA)350/oligo(dT)16 as template/primer preincubated followed by su...


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00612
BindingDB Entry DOI: 10.7270/Q2ZC86HB
More data for this
Ligand-Target Pair