Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50033866'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033866 (CHEMBL3358166) Show SMILES CC(NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)c1ccccn1 Show InChI InChI=1S/C24H22ClN3O3S/c1-14-10-15(2)12-18(11-14)32(30,31)23-19-13-17(25)7-8-21(19)28-22(23)24(29)27-16(3)20-6-4-5-9-26-20/h4-13,16,28H,1-3H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase L100I mutant assessed as reduction in enzyme activity				J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033866 (CHEMBL3358166) Show SMILES CC(NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)c1ccccn1 Show InChI InChI=1S/C24H22ClN3O3S/c1-14-10-15(2)12-18(11-14)32(30,31)23-19-13-17(25)7-8-21(19)28-22(23)24(29)27-16(3)20-6-4-5-9-26-20/h4-13,16,28H,1-3H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase assessed as reduction in enzyme activity				J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033866 (CHEMBL3358166) Show SMILES CC(NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)c1ccccn1 Show InChI InChI=1S/C24H22ClN3O3S/c1-14-10-15(2)12-18(11-14)32(30,31)23-19-13-17(25)7-8-21(19)28-22(23)24(29)27-16(3)20-6-4-5-9-26-20/h4-13,16,28H,1-3H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase K103N mutant assessed as reduction in enzyme activity				J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50033866 (CHEMBL3358166) Show SMILES CC(NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(C)cc(C)c1)c1ccccn1 Show InChI InChI=1S/C24H22ClN3O3S/c1-14-10-15(2)12-18(11-14)32(30,31)23-19-13-17(25)7-8-21(19)28-22(23)24(29)27-16(3)20-6-4-5-9-26-20/h4-13,16,28H,1-3H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase Y181I mutant assessed as reduction in enzyme activity				J Med Chem 57: 9945-57 (2014) Article DOI: 10.1021/jm5011622 BindingDB Entry DOI: 10.7270/Q2FB54K8
					More data for this Ligand-Target Pair