Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50088017'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50088017 (CHEMBL3427057) Show SMILES Cc1cc(cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(O)cc3)CC2)n1)C#N Show InChI InChI=1S/C26H28N6O3/c1-17-13-19(15-27)14-18(2)25(17)35-24-7-10-28-26(31-24)30-21-8-11-32(12-9-21)16-23(34)29-20-3-5-22(33)6-4-20/h3-7,10,13-14,21,33H,8-9,11-12,16H2,1-2H3,(H,29,34)(H,28,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 assessed as reduction in biotin-labeled dUTP incorporation into DNA using poly...				Eur J Med Chem 97: 1-9 (2015) Article DOI: 10.1016/j.ejmech.2015.04.050 BindingDB Entry DOI: 10.7270/Q22Z178R
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