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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50291982'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50291982
PNG
(CHEMBL4175661)
Show SMILES Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H20FN5/c1-16-13-20(19-5-7-21(26)8-6-19)14-17(2)24(16)30-23-11-12-28-25(31-23)29-22-9-3-18(15-27)4-10-22/h3-14H,1-2H3,(H2,28,29,30,31)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...

Eur J Med Chem 145: 726-734 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.016
BindingDB Entry DOI: 10.7270/Q21C20DV
More data for this
Ligand-Target Pair