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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50484323'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50484323
PNG
(CHEMBL1835496)
Show SMILES Cc1ccc(OCCn2ccc(=O)[nH]c2=O)c(Cc2ccccc2)c1
Show InChI InChI=1S/C20H20N2O3/c1-15-7-8-18(17(13-15)14-16-5-3-2-4-6-16)25-12-11-22-10-9-19(23)21-20(22)24/h2-10,13H,11-12,14H2,1H3,(H,21,23,24)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.80E+4n/an/an/an/an/an/an/an/a



Volgograd State Medical University

Curated by ChEMBL


Assay Description
Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase p66/p51 heterodimer using [8-3H]dGTP as substrate after 30 mins by ...

Bioorg Med Chem 19: 5794-802 (2011)


Article DOI: 10.1016/j.bmc.2011.08.025
BindingDB Entry DOI: 10.7270/Q2057JRG
More data for this
Ligand-Target Pair