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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50498755'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50498755
PNG
(CHEMBL3621389)
Show SMILES Cc1cc(cc(C)c1Oc1ccnc(n1)S(=O)(=O)CC(=O)Nc1ccc(Cl)c(Cl)c1)C#N
Show InChI InChI=1S/C21H16Cl2N4O4S/c1-12-7-14(10-24)8-13(2)20(12)31-19-5-6-25-21(27-19)32(29,30)11-18(28)26-15-3-4-16(22)17(23)9-15/h3-9H,11H2,1-2H3,(H,26,28)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 177n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase p66/p51 assessed as inhibition of biotin-dUTP incorporation using poly (rA)/oligo(dT)16 as template/primer i...

Eur J Med Chem 102: 215-22 (2015)


Article DOI: 10.1016/j.ejmech.2015.08.007
BindingDB Entry DOI: 10.7270/Q29Z97W1
More data for this
Ligand-Target Pair