Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 798 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 894 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in ... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50508778 (CHEMBL4450262) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti... | ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3 | |||||||||||
More data for this Ligand-Target Pair |