Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50508781'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair