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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50508785'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50508785
PNG
(CHEMBL4459834)
Show SMILES CCn1c2c(Oc3ccnc(Cl)c3)cccc2[nH]c1=O
Show InChI InChI=1S/C14H12ClN3O2/c1-2-18-13-10(17-14(18)19)4-3-5-11(13)20-9-6-7-16-12(15)8-9/h3-8H,2H2,1H3,(H,17,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.41E+4n/an/an/an/an/an/a



Stellenbosch University

Curated by ChEMBL


Assay Description
Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...

ACS Med Chem Lett 10: 196-202 (2019)


Article DOI: 10.1021/acsmedchemlett.8b00549
BindingDB Entry DOI: 10.7270/Q2CJ8HS3
More data for this
Ligand-Target Pair