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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50517390'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50517390
PNG
(CHEMBL4570889)
Show SMILES Cc1cc(cc(C)c1Oc1nc(NC2CCN(Cc3ccncc3)CC2)nc2CCSc12)C#N
Show InChI InChI=1S/C26H28N6OS/c1-17-13-20(15-27)14-18(2)23(17)33-25-24-22(7-12-34-24)30-26(31-25)29-21-5-10-32(11-6-21)16-19-3-8-28-9-4-19/h3-4,8-9,13-14,21H,5-7,10-12,16H2,1-2H3,(H,29,30,31)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 112n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of recombinant HIV1 reverse transcriptase using (DIG)-dUTP and biotin-labeled dNTPs as substrate after 1 hr by ELISA

J Med Chem 62: 1484-1501 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01656
BindingDB Entry DOI: 10.7270/Q29P351Z
More data for this
Ligand-Target Pair