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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50517397'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50517397
PNG
(CHEMBL4563462)
Show SMILES Cc1cc(cc(C)c1Oc1nc(NC2CCN(Cc3ccncc3)CC2)nc2CCCc12)C#N
Show InChI InChI=1S/C27H30N6O/c1-18-14-21(16-28)15-19(2)25(18)34-26-23-4-3-5-24(23)31-27(32-26)30-22-8-12-33(13-9-22)17-20-6-10-29-11-7-20/h6-7,10-11,14-15,22H,3-5,8-9,12-13,17H2,1-2H3,(H,30,31,32)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 73n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of recombinant HIV1 reverse transcriptase using (DIG)-dUTP and biotin-labeled dNTPs as substrate after 1 hr by ELISA

J Med Chem 62: 1484-1501 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01656
BindingDB Entry DOI: 10.7270/Q29P351Z
More data for this
Ligand-Target Pair