Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of dTMP by burst assay usin... | Antimicrob Agents Chemother 52: 2035-42 (2008) Article DOI: 10.1128/AAC.00083-08 BindingDB Entry DOI: 10.7270/Q2CZ39Z3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.44E+5 | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase M184V mutant assessed as incorporation of dTMP by burst assay usin... | Antimicrob Agents Chemother 52: 2035-42 (2008) Article DOI: 10.1128/AAC.00083-08 BindingDB Entry DOI: 10.7270/Q2CZ39Z3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair |