Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50299369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50299369 (CHEMBL575974 | N2-(2,3-dihydro-1H-inden-2-yl)-N4-p...) Show SMILES C1C(Cc2ccccc12)Nc1nc(Nc2ccccc2)nc(n1)N1CCNCC1 Show InChI InChI=1S/C22H25N7/c1-2-8-18(9-3-1)24-20-26-21(28-22(27-20)29-12-10-23-11-13-29)25-19-14-16-6-4-5-7-17(16)15-19/h1-9,19,23H,10-15H2,(H2,24,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of ROCK1 by IMAP assay				Bioorg Med Chem Lett 19: 6027-31 (2009) Article DOI: 10.1016/j.bmcl.2009.09.046 BindingDB Entry DOI: 10.7270/Q2668D7P
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