Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM169469'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169469 (US9079880, 2) Show SMILES COc1ccc(cc1Cl)C(=O)N[C@H](C1CC1)c1cccc(c1)C(=O)Nc1nc2CCN(C)Cc2s1 |r| Show InChI InChI=1S/C26H27ClN4O3S/c1-31-11-10-20-22(14-31)35-26(28-20)30-25(33)17-5-3-4-16(12-17)23(15-6-7-15)29-24(32)18-8-9-21(34-2)19(27)13-18/h3-5,8-9,12-13,15,23H,6-7,10-11,14H2,1-2H3,(H,29,32)(H,28,30,33)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
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