Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM169569'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169569 (US9079880, 102) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-n3ccnc3)sc2C1 |r| Show InChI InChI=1S/C30H32N6O2S/c1-34(2)24-12-13-25-27(18-24)39-30(32-25)33-28(37)22-6-3-5-21(17-22)26-7-4-15-36(26)29(38)20-8-10-23(11-9-20)35-16-14-31-19-35/h3,5-6,8-11,14,16-17,19,24,26H,4,7,12-13,15,18H2,1-2H3,(H,32,33,37)/t24-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169569 (US9079880, 102) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-n3ccnc3)sc2C1 |r| Show InChI InChI=1S/C30H32N6O2S/c1-34(2)24-12-13-25-27(18-24)39-30(32-25)33-28(37)22-6-3-5-21(17-22)26-7-4-15-36(26)29(38)20-8-10-23(11-9-20)35-16-14-31-19-35/h3,5-6,8-11,14,16-17,19,24,26H,4,7,12-13,15,18H2,1-2H3,(H,32,33,37)/t24-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair