Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM169577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169577 (US9079880, 110) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C32H34N6O3S/c33-20-23-6-2-7-28-25(23)11-13-38(28)32(40)37-12-3-8-27(37)21-4-1-5-22(18-21)30(39)35-31-34-26-10-9-24(19-29(26)42-31)36-14-16-41-17-15-36/h1-2,4-7,18,24,27H,3,8-17,19H2,(H,34,35,39)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169577 (US9079880, 110) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C32H34N6O3S/c33-20-23-6-2-7-28-25(23)11-13-38(28)32(40)37-12-3-8-27(37)21-4-1-5-22(18-21)30(39)35-31-34-26-10-9-24(19-29(26)42-31)36-14-16-41-17-15-36/h1-2,4-7,18,24,27H,3,8-17,19H2,(H,34,35,39)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair