Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM217322'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM217322 (US9302989, 547) Show SMILES O=C(Nc1ccc(cc1)-c1cccc2C(=O)NCc12)N1Cc2ccccc2C1 Show InChI InChI=1S/C23H19N3O2/c27-22-20-7-3-6-19(21(20)12-24-22)15-8-10-18(11-9-15)25-23(28)26-13-16-4-1-2-5-17(16)14-26/h1-11H,12-14H2,(H,24,27)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	179	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...				US Patent US9302989 (2016) BindingDB Entry DOI: 10.7270/Q2HH6HX1
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