Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50245914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50245914 (4-(2-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)benzo[d...) Show SMILES Nc1nccc(n1)-c1ccc2nc(oc2c1)C1COc2ccc(F)cc2C1 Show InChI InChI=1S/C20H15FN4O2/c21-14-2-4-17-12(8-14)7-13(10-26-17)19-24-16-3-1-11(9-18(16)27-19)15-5-6-23-20(22)25-15/h1-6,8-9,13H,7,10H2,(H2,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Florida Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6390-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.095 BindingDB Entry DOI: 10.7270/Q2T43SX6
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50245914 (4-(2-(6-fluoro-3,4-dihydro-2H-chromen-3-yl)benzo[d...) Show SMILES Nc1nccc(n1)-c1ccc2nc(oc2c1)C1COc2ccc(F)cc2C1 Show InChI InChI=1S/C20H15FN4O2/c21-14-2-4-17-12(8-14)7-13(10-26-17)19-24-16-3-1-11(9-18(16)27-19)15-5-6-23-20(22)25-15/h1-6,8-9,13H,7,10H2,(H2,22,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Florida Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 18: 6390-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.095 BindingDB Entry DOI: 10.7270/Q2T43SX6
					More data for this Ligand-Target Pair