Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50246455'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50246455 (2-(3,4-dihydro-2H-chromen-3-yl)-6-(pyridin-4-yl)-1...) Show SMILES C1Oc2ccccc2CC1c1nc2ccc(cc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C21H17N3O/c1-2-4-20-16(3-1)11-17(13-25-20)21-23-18-6-5-15(12-19(18)24-21)14-7-9-22-10-8-14/h1-10,12,17H,11,13H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Florida Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6390-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.095 BindingDB Entry DOI: 10.7270/Q2T43SX6
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50246455 (2-(3,4-dihydro-2H-chromen-3-yl)-6-(pyridin-4-yl)-1...) Show SMILES C1Oc2ccccc2CC1c1nc2ccc(cc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C21H17N3O/c1-2-4-20-16(3-1)11-17(13-25-20)21-23-18-6-5-15(12-19(18)24-21)14-7-9-22-10-8-14/h1-10,12,17H,11,13H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<6	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Florida Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 18: 6390-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.095 BindingDB Entry DOI: 10.7270/Q2T43SX6
					More data for this Ligand-Target Pair