Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50430365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50430365 (CHEMBL2333911) Show SMILES COc1ccc(C[C@H](N)c2nc3ccc(cc3c(=O)[nH]2)-c2cn[nH]c2)cc1OC |r| Show InChI InChI=1S/C21H21N5O3/c1-28-18-6-3-12(8-19(18)29-2)7-16(22)20-25-17-5-4-13(14-10-23-24-11-14)9-15(17)21(27)26-20/h3-6,8-11,16H,7,22H2,1-2H3,(H,23,24)(H,25,26,27)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...				Bioorg Med Chem Lett 23: 1592-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.109 BindingDB Entry DOI: 10.7270/Q2TD9ZQM
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