Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1' and Ligand = 'BDBM182592'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM182592 (US9145392, 293) Show SMILES CCOc1c(N)ncnc1N1CCC(CC1)c1nc(cn1CCN(C)C)-c1ccc(F)c(C)c1 Show InChI InChI=1S/C25H34FN7O/c1-5-34-22-23(27)28-16-29-25(22)32-10-8-18(9-11-32)24-30-21(15-33(24)13-12-31(3)4)19-6-7-20(26)17(2)14-19/h6-7,14-16,18H,5,8-13H2,1-4H3,(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	25
Merck Patent GmbH US Patent					Assay Description P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...				US Patent US9145392 (2015) BindingDB Entry DOI: 10.7270/Q2NZ86D2
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