Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1' and Ligand = 'BDBM50333488'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM50333488 (1-Benzo[4,5]furo[3,2-b]pyridin-8-yl-3-[5-tert-buty...) Show SMILES CC(C)(C)c1cc(C(=O)N2CCS(=O)(=O)CC2)c(NC(=O)Nc2ccc3oc4cccnc4c3c2)s1 Show InChI InChI=1S/C25H26N4O5S2/c1-25(2,3)20-14-17(23(30)29-9-11-36(32,33)12-10-29)22(35-20)28-24(31)27-15-6-7-18-16(13-15)21-19(34-18)5-4-8-26-21/h4-8,13-14H,9-12H2,1-3H3,(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of S6K1				Bioorg Med Chem Lett 21: 849-52 (2011) Article DOI: 10.1016/j.bmcl.2010.11.069 BindingDB Entry DOI: 10.7270/Q289163D
					More data for this Ligand-Target Pair