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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM386000'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase beta-1 [T412E]


(Homo sapiens (Human))		BDBM386000
PNG
(US10287300, Compound A7 | {2-(4-Chlorophenyl)-2-[4...)
Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H27ClN6/c1-25(2)13-18(15-3-5-16(21)6-4-15)26-9-11-27(12-10-26)20-17-7-8-22-19(17)23-14-24-20/h3-6,14,18H,7-13H2,1-2H3,(H,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair