Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM386001'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human))	BDBM386001 (US10287300, Compound A8 | {2-(4-Chlorophenyl)-2-[4...) Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCCc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H29ClN6/c1-26(2)14-19(16-5-7-17(22)8-6-16)27-10-12-28(13-11-27)21-18-4-3-9-23-20(18)24-15-25-21/h5-8,15,19H,3-4,9-14H2,1-2H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q26M394B
					More data for this Ligand-Target Pair