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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM386012'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase beta-1 [T412E]


(Homo sapiens (Human))		BDBM386012
PNG
(US10287300, Compound A18 | {2-(4-Chloro-3-fluoro-p...)
Show SMILES CN(C)CC(N1CCN(CC1)c1ncnc2NCCCc12)c1ccc(Cl)c(F)c1
Show InChI InChI=1S/C21H28ClFN6/c1-27(2)13-19(15-5-6-17(22)18(23)12-15)28-8-10-29(11-9-28)21-16-4-3-7-24-20(16)25-14-26-21/h5-6,12,14,19H,3-4,7-11,13H2,1-2H3,(H,24,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



University of Wisconsin at Madison



Assay Description
P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...

J Med Chem 51: 7243-52 (2008)


BindingDB Entry DOI: 10.7270/Q26M394B
More data for this
Ligand-Target Pair