Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM480488 (US10626113, Compound E | US10899756, Compound E) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 6.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0SFD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Homo sapiens (Human)) | BDBM480488 (US10626113, Compound E | US10899756, Compound E) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of Columbia University in the City of New York US Patent | Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react... | US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P | |||||||||||
More data for this Ligand-Target Pair |