Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SH2B adapter protein 2 (Human)	BDBM479324 ((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@H](C[C@H]5COc34)OC3COC3)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C27H36N6O5S/c1-16-24(28)27(15-37-16)3-6-32(7-4-27)25-20(11-34)31-22(9-30-25)39-21-2-5-29-26-23(21)36-12-17-8-18(10-33(17)26)38-19-13-35-14-19/h2,5,9,16-19,24,34H,3-4,6-8,10-15,28H2,1H3/t16-,17-,18-,24+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W7X
					More data for this Ligand-Target Pair