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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479330'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
SH2B adapter protein 2


(Human)		BDBM479330
PNG
((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...)
Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@](C)(O)C[C@H]5COc34)nc2CO)[C@@H]1N |r|
Show InChI InChI=1S/C25H34N6O4S/c1-15-21(26)25(14-35-15)4-7-30(8-5-25)22-17(11-32)29-19(10-28-22)36-18-3-6-27-23-20(18)34-12-16-9-24(2,33)13-31(16)23/h3,6,10,15-16,21,32-33H,4-5,7-9,11-14,26H2,1-2H3/t15-,16-,21+,24+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a


TBA

Assay Description
The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2VT1W7X
More data for this
Ligand-Target Pair