Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479334'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SH2B adapter protein 2 (Human)	BDBM479334 ((6aS,8R)-4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- ...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@@H](C[C@H]5COc34)OC(N)=O)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C25H33N7O5S/c1-14-21(26)25(13-36-14)3-6-31(7-4-25)22-17(11-33)30-19(9-29-22)38-18-2-5-28-23-20(18)35-12-15-8-16(10-32(15)23)37-24(27)34/h2,5,9,14-16,21,33H,3-4,6-8,10-13,26H2,1H3,(H2,27,34)/t14-,15-,16+,21+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W7X
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