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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479339'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
SH2B adapter protein 2


(Human)		BDBM479339
PNG
(4-((5-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[...)
Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5CCS(=O)(=O)CC5COc34)nc2CO)[C@@H]1N |r|
Show InChI InChI=1S/C24H32N6O5S2/c1-15-21(25)24(14-35-15)3-6-29(7-4-24)22-17(11-31)28-19(10-27-22)36-18-2-5-26-23-20(18)34-12-16-13-37(32,33)9-8-30(16)23/h2,5,10,15-16,21,31H,3-4,6-9,11-14,25H2,1H3/t15-,16?,21+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a


TBA

Assay Description
The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2VT1W7X
More data for this
Ligand-Target Pair