Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479345'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SH2B adapter protein 2 (Human)	BDBM479345 ((3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5...) Show SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5C[C@@H](COCC6COC6)C[C@H]5COc34)nc2CO)[C@@H]1N |r| Show InChI InChI=1S/C29H40N6O5S/c1-18-26(30)29(17-40-18)3-6-34(7-4-29)27-22(11-36)33-24(9-32-27)41-23-2-5-31-28-25(23)39-16-21-8-19(10-35(21)28)12-37-13-20-14-38-15-20/h2,5,9,18-21,26,36H,3-4,6-8,10-17,30H2,1H3/t18-,19-,21-,26+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W7X
					More data for this Ligand-Target Pair