Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'SH2B adapter protein 2' and Ligand = 'BDBM479349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SH2B adapter protein 2 (Human)	BDBM479349 ((3-((S)-5-amino-13-oxa-9- azadispiro[3.1.56.24]tri...) Show SMILES COC[C@H]1C[C@H]2COc3c(Sc4cnc(N5CCC6(COC7(CCC7)[C@H]6N)CC5)c(CO)n4)ccnc3N2C1 |r| Show InChI InChI=1S/C28H38N6O4S/c1-36-15-18-11-19-16-37-23-21(3-8-30-25(23)34(19)13-18)39-22-12-31-24(20(14-35)32-22)33-9-6-27(7-10-33)17-38-28(26(27)29)4-2-5-28/h3,8,12,18-19,26,35H,2,4-7,9-11,13-17,29H2,1H3/t18-,19-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W7X
					More data for this Ligand-Target Pair